DAY 1 Monday 7th December SESSION 1
SESSION 1 CHAIRS:
Prof Benedict Michael, Chair Scientific Advisory Panel, Encephalitis International & University of Liverpool, UK
Assist Prof Matteo Gastaldi
Research Unit in Pavia & University of Pavia, Italy , Chair of Encephalitis Conference Committee
8:30: REGISTRATION
9:25: WELCOME
9:30: Basic Clinical Introduction to Infectious Encephalitis , Dr Nicholas Davies, Chelsea and Westminster, Charing Cross, and the Royal Marsden Hospitals, London, UK
10:15: Basic Clinical Introduction to Autoimmune Encephalitis , Dr Sophie Binks, Nuffield Department of Clinical Neurosciences, University of Oxford, UK
11:00: BREAK
11:20: Clinical Case Presentation, Dr James Sejvar, University of Pittsburgh, USA & Assoc Prof Maarten Titulaer, Erasmus University Medical Center, The Netherlands
12:20 : How to Get Your Grant or Fellowship, Dr Greta Wood, University of Liverpool, UK
13:00: LUNCH/SATELLITE MEETING
13.30: Poster viewing
14:20: Data Blitz Session 2 (to include 20 minute break)
DAY 1 Monday 7th December SESSION 2
14:25: Beyond infection: evaluating autoimmune encephalitis in pediatric febrile coma in Malawi, Dr Mary Karalius, University of California, San Francisco, USA
14:35: Antibody glycosylation profiles are
compartmentalized and associate with trigger
and outcome in anti-NMDAR encephalitis Ms Laura Marmolejo, University of Barcelona,
Spain and Caixa Research Institute (CRI), Barcelona, Spain
14:45: Characterization of relapses in anti-NMDAR encephalitis, Dr Tessa M. Bienfait, Erasmus MC, The Netherlands
14:55: Are we listening to patients with encephalitis? What their narratives reveal about diagnosis and care, Anne Caroline Marcos Msc, Instituto Oswaldo, Cruz (IOC/Fiocruz), Brazil
15:05: Cognitive profiles and longitudinal recovery in autoimmune limbic encephalitis: a
comparative antibody-stratified cohort study
Dr Francesco Deleo, Fondazione IRCCS Istituto Neurologico Carlo Besta, Italy
15:15: Circulating B cells in patients with LGI1 and GAD65 encephalitis Suzanne Franken MSc, Erasmus MC, The Netherlands
15:25: BREAK
15:45: Early recognition of encephalitis in children: knowledge, practices, and barriers among pediatric nursing staff at CHU Ibn Rochd, Casablanca, Morocco, Mr Hamza Romandi, Ibn Rochd University Hospital Center, Morocco
15:55: Latent Phenotypes and Prognosis in Severe Encephalitis, Dr Chiara Risso, Universite Paris Cite, France, Diagnostic utility of Phage
16:05: ImmunoPrecipitation Sequencing in
neuroinfectious and neuroinflammatory
diseases, Ms Barbara Nieuwenhuijsen, Amsterdam University Medical Center, The Netherlands
16:15: Brain network changes in paediatric
autoimmune encephalitis and ADEM: evidence
from resting-state fMRI, Dr Meirvaan Basra, Aston University, Birmingham, UK
16:25: CNS-migratory GAD65-specific B cells drive IIFN-γresponses in GAD65 autoimmunity,
Jan Bartosch MSc, LMU Klinikum, Germany
16:35: The diagnostic yield of whole body [18F]FDG PET/CT in the investigation of neurological conditions, Dr James Varley, Imperial College Healthcare, NHS Trust London, UK
16:45: Efficacy and safety of bortezomib in paediatric anti-NMDAR encephalitis: a retrospective international cohort study, Dr Alessandro Santagostino Barbone, University of Genoa, Italy; Evelina London Children’s Hospital, UK
17:00: DRINKS RECEPTION/POSTER PRESENTATIONS
18:00: LONDON CHRISTMAS LIGHTS WALKING TOUR
DAY 2 Tuesday 8th December SESSION 1
8:00 Registration
8:30 Poster Presentations
9:10 Welcome: Prof Benedict Michael, Chair Advisory Scientific Panel, Encephalitis International & University of Liverpool, UK and Dr Ava Easton MBE, CEO Encephalitis International & University of Liverpool, UK
9:15: KEYNOTE LECTURE 1: Immunotherapies for Infectious Encephalitis, Dr Irene Cortese, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, USA
9:40: Discussion
9:45: Long-term outcomes of childhood encephalitis in Australia: Burden and predictors from the Australian Childhood Encephalitis (ACE) prospective multicentre cohort, Dr Gautam J Rao, University of Sydney, Australia
9:55: Discussion
10:00: Intrathecal immune signatures in IgLON5 disease, Dr Martijn van Duijn, Erasmus MC University, Medical Centre, The Netherlands
10:10: Discussion
10:15: Identification of Leiomodin-1 autoantibody as a novel biomarker in cryptogenic new-onset refractory status epilepticus, Dr Soo Jean Shin, Seoul National University, Hospital, South Korea
10:25: Discussion
10:30: Microglial depletion drives peripheral immune cell repopulation of the brain which protects the central nervous system from bacterial meningoencephalitis, Prof Federico Iovino, Karolinska Institute, Sweden
10:40: Discussion
10:45: A Seat at the Table — or Building a New Table? The evolving role of Encephalitis International in global research, Dr Ava Easton MBE, Encephalitis International & University of Liverpool, UK
11:00: Discussion
11:05: BREAK/POSTER VIEWING
DAY 2 Tuesday 8th December SESSION 2
11:25: Intercompartmental B cells in autoimmune encephalitis after herpes simplex virus encephalitis reveal mechanisms of autoantibody production, Dr Jonathan Cleaver, University of Oxford, UK
11:35: Discussion
11:40: Baseline characteristics and treatment
heterogeneity in NMDAR-IgG autoimmune encephalitis: an international multicenter analysis from the clinical outcomes in
autoimmune encephalitis study (COAST) ,Assoc Prof Amy Kunchok, Cleveland Clinic, USA
11:50: Discussion
11:55: Diagnostic, treatment, and follow-up practice variation in encephalitis of unknown etiology: the neuroinfections emerging in the Americas Study (NEAS) In Colombia, Dr Maria Reyes-Mantilla, Hospital Simon Bolivar, Colombia
12:05: Discussion
12:10: CSF host transcriptomics predicts infectious causes and outcomes of febrile coma in Malawian children, Dr Mary Karalius, University of California, USA
12:20: Discussion
12:25: GUEST LECTURE 2: From Acute Care to Real Life: Improving Outcomes That Matter to Patients, Sophia Rekers MSc, Berlin School of Mind and Brain, Charité - Universitätsmedizin Berlin, Germany
12:50: Discussion
12:55: LUNCH/POSTER VIEWING
DAY 2 Tuesday 8th December SESSION 3
14:10: KEYNOTE LECTURE 2: Where You Live Shouldn’t Decide if You Survive: Encephalitis in Low- and Middle Income Countries, Dr Jamil Said, Moi Teaching and Referal Hospital
(MTRH) and Moi University School of Medicine (MUSOM); AMPATH, Kenya
14:35: Discussion
14:40: Single-cell immune profiling reveals shared and subtype-specific immune signatures across autoimmune encephalitis syndromes, Dr Daniela Esser, University Hospital Schleswig-Holstein, Germany
14:50: Discussion
14:55: INSPIRE: intimacy, sex, and partnership in
recovery from encephalitis, Ms Laora Tobelaim-Chimchirian MSc, King’s College London, UK
15:05: Discussion
15:10: BREAK/POSTER VIEWING
DAY 2 Tuesday 8th December SESSION 4
15:30: Diverging recovery trajectories in LGI1 and NMDA receptor encephalitis: a longitudinal outcome analysis with group-specific predictor modelling, Dr Juri Habicht, Charité – Universitätsmedizin Berlin, Germany
15:45: NeuroQuiz
16:30: INVITED GUEST LECTURE: When Antibodies Are Absent: Progress and Priorities in Seronegative Autoimmune Encephalitis, Prof Soon-Tae Lee, Seoul National University, Hospital, Seoul National University College of Medicine, Seoul, South Korea
16:55: Discussion
17:00: Encephalitis International: Our Year
Phillippa Chapman, Encephalitis International, UK
17:05: Awards and call to action
Prof Benedict Michael and Dr Ava Easton
17:15: DRINKS AND NETWORKING RECEPTION