Seed Funding: France

Project title: Markers of neuroinflammatory activity in autoimmune encephalitis

Project lead: Dr Chloe Bost

Department and institution: Immunology laboratory, Toulouse University Hospital

Awarded in 2023

Autoimmune encephalitis field has experienced great improvements in knowledge in recent years, both from a diagnostic point of view and understanding of the mechanisms underlying these pathologies. However, few relevant tools are available for monitoring patients and especially for assessing and adapting the therapeutic response.

Our project is to find, in the blood or CSF, a biomarker making it possible to monitor the neuroinflammatory activity of the disease. We identified 2 promising markers in a preliminary study that we will evaluate in a larger study. This is in order to be able to adapt the treatment of patients and limit side effects.