Epidemiology Expand Autoimmune Encephalitis Epidemiology and a comparison to Infectious Encephalitis Dubey D, Pittock SJ, Kelly CR, McKeon A, Lopez-Chiriboga AS, Lennon V, Gadoth A, Smith CY, Bryant SC, Klein CJ, Aksamit AJ, Toledano M, Boeve BF, Tilemma JM, Flanagan EP Ann Neurol. 2018 Jan 2. doi: 10.1002/ana.25131. [Epub ahead of print] Epidemiology of Meningitis and Encephalitis in the United States from 2011-2014. Rodrigo Hasbun, Ning Rosenthal, JM Balada-Llasat, Jessica Chung, Steve Duff, Samuel Bozzette, Louise Zimmer, Christine C. Ginocchio Clin Infect Dis. 2017 Apr 17. doi: 10.1093/cid/cix319. 30-year trends in admission rates for encephalitis in children in England and effect of improved diagnostics and measles-mumps-rubella vaccination: a population-based observational study. Iro MA, Sadarangani M, Goldacre R, Nickless A, Pollard AJ, Goldacre MJ. Lancet Infect Dis. 2017 Apr;17(4):422-430. doi: 10.1016/S1473-3099(17)30114-7. Epub 2017 Mar 2.
Infectious encephalitis Expand Diagnostic approach to encephalitis and meningoencephalitis in adult returning travellers Kenfak A., Eperon G., Schibler M, et al. Clinical Microbiology and Infection 25 (2019) 415e421 The neurological complications of chikungunya virus: A systematic review Mehta R, Gerardin P, de Brito CAA, Soares CN, Ferreira MLB, Solomon T Rev Med Virol. 2018 May;28(3):e1978. doi: 10.1002/rmv.1978. Epub 2018 Apr 19. Japanese encephalitis - the prospects for new treatments Turtle L, Solomon T. Nat Rev Neurol. 2018 Apr 26;14(5):298-313. doi: 10.1038/nrneurol.2018.30. Viral Encephalitis of Unknown Cause: Current Perspective and Recent Advances. Kennedy, Peter G. E., Phenix-Lan Quan, Lipkin, W. Ian Viruses (1999-4915). Jun2017, Vol. 9 Issue 6, p1-8. 8p. Diagnostic Pathways as Social and Participatory Practices: The Case of Herpes Simplex Encephalitis Jessie Cooper , Ciara Kierans, Sylviane Defres, Ava Easton, Rachel Kneen, Tom Solomon PLoS ONE 11(3): e0151145. doi:10.1371/journal.pone.0151145 Chikungunya virus-associated encephalitis. A cohort study on La Reunion Island, 2005-2009 Patrick Gerardin, Therese Couderc, Marc Bintner, Patrice Tournebize, Michel Renouil, Jerome Lemant, Veronique Boisson, Gianandrea Borgherini, Frederik Staikowsky, Frederic Schramm, Marc Lecuit, Alain Michault On behalf of the Encephalchik Study Group Neurology 86 January 5, 2016 Normocellular CSF in herpes simplex encephalitis Saraya AW, Wacharapluesadee S, Petcharat S, Sittidetboripat N, Ghai S, Wilde H, Hemachudha T BMC Res Notes 2016 Feb 15;9(1):95. doi: 10.1186/s13104-016-1922-9. Fatal encephalitis associated with Zika virus infection in an adult Cristiane N. Soares (PhD), Patricia Brasil (PhD) , Raquel Medialdea Carrera (MSc), Patricia Sequeira (PhD), Ana Bispo de Filippis , Vitor A. Borges, Fernando Theophilo (MD, PhD), Mark A. Ellul (MRCP), Tom Solomon (FRCP) Journal of Clinical Virology 83 (2016) 63-65 Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis Sofia Morfopoulou, Edward T. Mee, Sarah M. Connaughton, Julianne R. Brown, Kimberly Gilmour, WK Kling Chong, W. Paul Duprex, Deborah Ferguson, Mike Hubank, Ciaran Hutchinson, Marios Kaliakatsos, Stephen McQuaid, Simon Paine, Vincent Plagnol, Christopher Ruis, Alex Virasami, Hong Zhan, Thomas S. Jacques, Silke Schepelmann, Waseem Qasim, Judith Breuer Acta Neuropathol (2016). doi:10.1007/s00401-016-1629-y Human Coronavirus OC43 Associated with Fatal Encephalitis Morfopoulou S, Brown JR, Davies EG, Anderson G, Virasami A, Qasim W, Chong WK, Hubank M, Plagnol V, Desforges M, Jacques TS, Talbot PJ, Breuer J. N Engl J Med 2016; 375:497-498August 4, 2016DOI: 10.1056/NEJMc1509458
Autoimmune encephalitis Expand Evaluation of seizure treatment in anti-LGI1, anti-NMDAR, and anti-GABABR encephalitis Marienke A.A.M. de Bruijn, Agnes van Sonderen Neurology May 7, 2019 92:e2185-e2196; published ahead of print April 12, 2019 OPEN ACCESS ARTICLE The psychopathology of NMDAR-antibody encephalitis in adults: a systematic review and phenotypic analysis of individual patient data Adam Al-Diwani, Adam Handel, Leigh Townsend, et al. 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Prevalence and clinical characteristics of serum neuronal cell surface antibodies in first-episode psychosis: a case-control study Dr Belinda R Lennox, Emma C Palmer-Cooper, Thomas Pollak, Jane Hainsworth, Jacqui Marks, Leslie Jacobson, Bethan Lang, Hannah Fox, Berne Ferry, Linda Scoriels, Hannah Crowley, Peter B Jones, Paul J Harrison, Angela Vincent, on behalf of the PPiP study team The Lancet Psychiatry (2016) DOI: 10.1016/S2215-0366(16)30375-3 Human neurexin-3α antibodies associate with encephalitis and alter synapse development Nuria Gresa-Arribas, Jesús Planagumà, Mar Petit-Pedrol, Izumi Kawachi, Shinichi Katada,Carol A. Glaser, Mateus M. 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Diagnosis, treatment and outcomes Expand Acute encephalitis – diagnosis and management Mark Ellul, Tom Solomon Clinical Medicine 2018 Vol 18, No 2: 155–9 Intravenous immunoglobulin for the treatment of childhood encephalitis. Iro MA, Martin NG, Absoud M, Pollard AJ. Cochrane Database Syst Rev. 2017 Oct 2;10:CD011367. doi: 10.1002/14651858.CD011367.pub2. The inter-rater reliability and prognostic value of coma scales in Nepali children with acute encephalitis syndrome Ray S, Rayamajhi A, Bonnett LJ, Solomon T, Kneen R, Griffiths MJ. Paediatr Int Child Health. 2017 Nov 16:1-6. Diagnostic Pathways as Social and Participatory Practices: The Case of Herpes Simplex Encephalitis Jessie Cooper, Ciara Kierans, Sylviane Defres, Ava Easton, Rachel Kneen, Tom Solomon PLOS ONE | DOI:10.1371/journal.pone.0151145 March 9, 2016 Neuroimaging in encephalitis: analysis of imaging findings and interobserver agreement J. Granerod, N.W.S. Davies, W. Mukonoweshuro, A. Mehta, K. Das, M. Lim, T. Solomon, S. Biswas, L. Rosella, D.W.G. Brown, N.S. Crowcroft on behalf of the UK Public Health England Aetiology of Encephalitis Study Group Clinical Radiology (2016), http://dx.doi.org/10.1016/j.crad.2016.03.015 Increased rates of sequelae post-encephalitis in individuals attending primary care practices in the United Kingdom: a population-based retrospective cohort study Julia Granerod, Nicholas W. S. Davies, Parashar P. Ramanuj, Ava Easton, David W. G. Brown, Sara L. Thomas J Neurol. 2016 Oct 20. [Epub ahead of print) ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial. Iro MA, Sadarangani M, Absoud M, et al. BMJ Open 2016;6:e012356. doi:10.1136/bmjopen-2016- 012356
Recovery and rehabilitation Expand Care beyond the hospital ward: understanding the socio-medical trajectory of herpes simplex virus encephalitis Jessie Cooper, Ciara Kierans, Sylviane Defres, Ava Easton, Rachel Kneen, Tom Solomon and on behalf of ENCEPH-UK study group BMC Health Services Research (2017) 17:646 DOI 10.1186/s12913-017-2608-2 Neurobehavioral outcomes in autoimmune encephalitis Yeshokumar AK, Gordon-Lipkin E, Arenivas A, Cohen J, Venkatesan A, Saylor D, Probasco JC. J Neuroimmunol. 2017 Aug 31. pii: S0165-5728(17)30274-6. doi: 10.1016/j.jneuroim.2017.08.010. [Epub ahead of print]
Pathogenesis of encephalitis Expand Characteristic Cytokine and Chemokine Profiles in Encephalitis of Infectious, Immune-Mediated, and Unknown Aetiology Michael BD, Griffiths MJ, Granerod J, Brown D, Davies NWS, Borrow R, Solomon T PLoS One. 2016;11(1):e0146288. doi: 10.1371/journal.pone.0146288 A complement-microglial axis drives synapse loss during virus-induced memory impairment Michael J. Vasek, Charise Garber, Denise Dorsey, Douglas M. Durrant, Bryan Bollman, Allison Soung, Jinsheng Yu, Carlos Perez-Torres, Arnaud Frouin, Daniel K. Wilton, Kristen Funk, Bette K. DeMasters, Xiaoping Jiang, James R. Bowen, Steven Mennerick, John K. Robinson, Joel R. Garbow, Kenneth L. Tyler, Mehul S. Suthar,Robert E. Schmidt, Beth Stevens, Robyn S. Klein Nature 534, 538-543 (23 June 2016) doi:10.1038/nature18283 Herpes simplex encephalitis is linked with selective mitochondrial damage; a post-mortem and in vitro study Wnek, M., Ressel, L., Ricci, E. et al. Acta Neuropathol (2016) 132: 433. doi:10.1007/s00401-016-1597-2