Covid-19 Observational Studies

Observational study

Frontera J.A., Sabadia S., Lalchan R., et al. (2020) A Prospective Study of Neurologic Disorders in Hospitalized COVID-19 Patients in New York City. Neurology Oct 2020, 10.1212/WNL.0000000000010979; DOI: 10.1212/WNL.0000000000010979

Alexopoulos H., Magira E., Bitzogli K., et al. (2020) Anti–SARS-CoV-2 antibodies in the CSF, blood-brain barrier dysfunction, and neurological outcome. Studies in 8 stuporous and comatose patients. Neurol Neuroimmunol Neuroinflamm 2020;7:e893. doi:10.1212/NXI.0000000000000893

Guilmot A, Maldonado Slootjes S, Sellimi A, et al. Immune-mediated neurological syndromes in SARS-CoV-2-infected patients [published online ahead of print, 2020 Jul 30]. J Neurol. 2020;1-7. doi:10.1007/s00415-020-10108-x

Pilotto et al. The clinical spectrum of encephalitis in COVID-19 disease: the ENCOVID multicentre study. MedRxiv (preprint). https://doi.org/10.1101/2020.06.19.20133991

Paterson RW, Brown RL, Benjamin L. et al. The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings, Brain, , awaa240, doi.org/10.1093/brain/awaa240

Varatharaj A., Thomas N., and Ellul M., et al. (2020) UK-Wide Surveillance of Neurological and Neuropsychiatric Complications of COVID-19: The First 153 Patients. http://dx.doi.org/10.2139/ssrn.3601761

Ferrarese C., Silani V., Priori A. An Italian multicenter retrospective-prospective observational study on neurological manifestations of COVID-19 (NEUROCOVID). Neurological Sciences; 41: 1355-1359 https://doi.org/10.1007/s10072-020-04450-1

Frontera J., Mainali S., Fink E.L., et al. (2020) Global Consortium Study of Neurological Dysfunction in COVID‑19 (GCS‑NeuroCOVID): Study Design and Rationale. Neurocrit Care https://doi.org/10.1007/s12028-020-00995-3

Latest

NMDAR antibody encephalitis

NMDAR antibody encephalitis is an autoimmune disease that causes psychiatric features, confusion, memory loss and seizures followed by a movement disorder, loss of consciousness and changes in blood pressure, heart rate and temperature.
Herpes Simplex virus encephalitis

Herpes simplex encephalitis is a type of infectious encephalitis which happens when herpes simplex virus (HSV) enters the brain. Usually, it begins with ‘flu-like’ symptoms followed by neurological deterioration, which may include personality and behavioural changes, seizures, weakness and difficulties in communication.
What is encephalitis?

Encephalitis is an inflammation of the brain caused by an infection or through the immune system attacking the brain in error.
Guidelines for recovery

No two people with encephalitis have the same outcomes. People recover at different paces. Recovery can be helped by having lots of rest, good nutrition, helpful social network and support from professionals.
Limbic encephalitis

The term ‘limbic encephalitis’ (LE) describes the condition when limbic areas of the brain are inflamed (swollen) and consequently not functioning properly. Most forms of LE fall into two main categories: infectious encephalitis and autoimmune encephalitis.
Death from encephalitis

Encephalitis is a serious neurological condition and unfortunately, despite improvements in specific and more supportive treatments such as excellent intensive care management, encephalitis still has a high mortality (death) rate.
West Nile encephalitis

West Nile encephalitis is a type of infectious encephalitis caused by West Nile virus. People usually become infected after being bitten by a mosquito, which has fed on an infected bird.
Encephalitis: after-effects, recovery and rehabilitation

This booklet provides key information about the type of issues that people may have after encephalitis, why rehabilitation/support from professionals and families are important and what options for self-help are available.
Emotional and behavioural changes

Following encephalitis, some people may experience emotional and behavioural changes including low mood, increased anxiety, depression, mood swings, frustration, aggression, impulsivity, disinhibition, and/or poor emotional regulation.
Get support

Our Support Service is here to help you with any questions about encephalitis, recovery and rehabilitation or emotional support.