Diagnosis, treatment and outcomes

Acute encephalitis – diagnosis and management

Mark Ellul, Tom Solomon

Clinical Medicine 2018 Vol 18, No 2: 155–9

Intravenous immunoglobulin for the treatment of childhood encephalitis.

Iro MA, Martin NG, Absoud M, Pollard AJ.

Cochrane Database Syst Rev. 2017 Oct 2;10:CD011367. doi: 10.1002/14651858.CD011367.pub2.

The inter-rater reliability and prognostic value of coma scales in Nepali children with acute encephalitis syndrome

Ray S, Rayamajhi A, Bonnett LJ, Solomon T, Kneen R, Griffiths MJ.

Paediatr Int Child Health. 2017 Nov 16:1-6.

Diagnostic Pathways as Social and Participatory Practices: The Case of Herpes Simplex Encephalitis

Jessie Cooper, Ciara Kierans, Sylviane Defres, Ava Easton, Rachel Kneen, Tom Solomon

PLOS ONE | DOI:10.1371/journal.pone.0151145 March 9, 2016

Neuroimaging in encephalitis: analysis of imaging findings and interobserver agreement

J. Granerod, N.W.S. Davies, W. Mukonoweshuro, A. Mehta, K. Das, M. Lim, T. Solomon, S. Biswas, L. Rosella, D.W.G. Brown, N.S. Crowcroft on behalf of the UK Public Health England Aetiology of Encephalitis Study Group

Clinical Radiology (2016), http://dx.doi.org/10.1016/j.crad.2016.03.015

Increased rates of sequelae post-encephalitis in individuals attending primary care practices in the United Kingdom: a population-based retrospective cohort study

Julia Granerod, Nicholas W. S. Davies, Parashar P. Ramanuj, Ava Easton, David W. G. Brown, Sara L. Thomas

J Neurol. 2016 Oct 20. [Epub ahead of print)

ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial.

Iro MA, Sadarangani M, Absoud M, et al.

BMJ Open 2016;6:e012356. doi:10.1136/bmjopen-2016- 012356

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NMDAR antibody encephalitis

NMDAR antibody encephalitis is an autoimmune disease that causes psychiatric features, confusion, memory loss and seizures followed by a movement disorder, loss of consciousness and changes in blood pressure, heart rate and temperature.
Herpes Simplex virus encephalitis

Herpes simplex encephalitis is a type of infectious encephalitis which happens when herpes simplex virus (HSV) enters the brain. Usually, it begins with ‘flu-like’ symptoms followed by neurological deterioration, which may include personality and behavioural changes, seizures, weakness and difficulties in communication.
What is encephalitis?

Encephalitis is an inflammation of the brain caused by an infection or through the immune system attacking the brain in error.
Guidelines for recovery

No two people with encephalitis have the same outcomes. People recover at different paces. Recovery can be helped by having lots of rest, good nutrition, helpful social network and support from professionals.
Limbic encephalitis

The term ‘limbic encephalitis’ (LE) describes the condition when limbic areas of the brain are inflamed (swollen) and consequently not functioning properly. Most forms of LE fall into two main categories: infectious encephalitis and autoimmune encephalitis.
Death from encephalitis

Encephalitis is a serious neurological condition and unfortunately, despite improvements in specific and more supportive treatments such as excellent intensive care management, encephalitis still has a high mortality (death) rate.
Encephalitis: after-effects, recovery and rehabilitation

This booklet provides key information about the type of issues that people may have after encephalitis, why rehabilitation/support from professionals and families are important and what options for self-help are available.
West Nile encephalitis

West Nile encephalitis is a type of infectious encephalitis caused by West Nile virus. People usually become infected after being bitten by a mosquito, which has fed on an infected bird.
Emotional and behavioural changes

Following encephalitis, some people may experience emotional and behavioural changes including low mood, increased anxiety, depression, mood swings, frustration, aggression, impulsivity, disinhibition, and/or poor emotional regulation.
Get support

Our Support Service is here to help you with any questions about encephalitis, recovery and rehabilitation or emotional support.